Sphinx

[] [bioRxiv]

Sphinx: modeling transcriptional heterogeneity in single-cell RNA-Seq


“The significance of single cell transcription resides not only in the cumulative expression strength of the cell population but also in its heterogeneity.” ” A new model that improves the detection of changes in the transcriptional heterogeneity pattern of RNAseq data using two heterogeneity parameters: “burst proportion” and “burst magnitude””

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