Pan-Cancer Driver Protein Interaction

[PMID:26485003] [PLoS Computational Biology]

A Pan-Cancer Catalogue of Cancer Driver Protein Interaction Interfaces

“mutation patterns of the protein-protein interaction (PPI) interfaces from 10,028 proteins in a pan-cancer cohort of 5,989 tumors from 23 projects of The Cancer Genome Atlas (TCGA) to find interfaces enriched in somatic missense mutations.”

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