Subclonal Resistance

[PMID:26483300] [Nature Reviews Clinical Oncology]

The influence of subclonal resistance mutations on targeted cancer therapy

“Moving forward, several short-term actions could be implemented coordinately to forestall the onset of drug resistance. These include: early detection of subclonal drug-resistance mutations; routine implementation of high-sensitivity liquid biopsies; monitoring patients for early disease recurrence; development of effective protocols for simultaneous treatment with multiple drugs; and, most importantly, continued efforts to expand our repertoire of targeted therapeutic options.”


Leave a Reply

Fill in your details below or click an icon to log in: Logo

You are commenting using your account. Log Out /  Change )

Google+ photo

You are commenting using your Google+ account. Log Out /  Change )

Twitter picture

You are commenting using your Twitter account. Log Out /  Change )

Facebook photo

You are commenting using your Facebook account. Log Out /  Change )


Connecting to %s