Month: November 2015

Cancer RNA-Seq Nexus

[PMID:26602695] [Nucleic Acids Research]

Cancer RNA-Seq Nexus: a database of phenotype-specific transcriptome profiling in cancer cells

“features: (i) large-scale and comprehensive data archives and analyses, including coding-transcript profiling, long non-coding RNA (lncRNA) profiling and coexpression networks; (ii) phenotype-oriented data organization and searching and (iii) the visualization of expression profiles, differential expression and regulatory networks.”


Germline Findings in Tumor-Only Sequencing

[PMID:26590952] [Journal of National Cancer Institute]

Germline Findings in Tumor-Only Sequencing: Points to Consider for Clinicians and Laboratories

“Analysis of the cancer genome is most informative when paired with germline genomic DNA to delineate inherited and somatic variants. Although tumor-only analysis remains the most common methodology for numerous reasons, it holds the potential to identify clinically significant germline variants.”