Non-Darwinian Cell Evolution

[PMID:26561581] [Proceedings of the National Academy of Sciences]

Extremely high genetic diversity in a single tumor points to prevalence of non-Darwinian cell evolution

“Here, from a hepatocellular carcinoma (HCC) tumor, we evaluated multiregional samples from the tumor, using either whole-exome sequencing (WES) (n = 23 samples) or genotyping (n = 286)” “For sequencing, the average read depth was 74.4×”. Work by Chung-I Wu.

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