Pan-Cancer Intratumor Heterogeneity

[PMID:26618723] [Nature Medicine]

Pan-cancer analysis of the extent and consequences of intratumor heterogeneity


“used the bioinformatics tools ‘expanding ploidy and allele frequency on nested subpopulations’ (EXPANDS) and PyClone to detect clones that are present at a ≥10% frequency in 1,165 exome sequences from tumors in The Cancer Genome Atlas.”

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