RNA-seq Fusion Meta-caller

[PMID:26582927] [Nucleic Acids Research]

Comprehensive evaluation of fusion transcript detection algorithms and a meta-caller to combine top performing methods in paired-end RNA-seq data

“Fifteen fusion transcript detection tools were compared using three synthetic data sets” “No single method dominantly performed the best but SOAPfuse generally performed well, followed by FusionCatcher and JAFFA.” “a meta-caller algorithm by combining top performing methods to re-prioritize candidate fusion transcripts with high confidence that can be followed by experimental validation.”

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