Lung Cancer Somatic Variants

[PMID:27158780] [Nature Genetics]

Distinct patterns of somatic genome alterations in lung adenocarcinomas and squamous cell carcinomas

Work from Matthew Meyerson and Cancer Genome Atlas Research Network. “examined the exome sequences and copy number profiles of 660 lung ADC and 484 lung SqCC tumor–normal pairs. Recurrent alterations in lung SqCCs were more similar to those of other squamous carcinomas than to alterations in lung ADCs.”

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