Single-cell Epigenetic Heterogeneity

[PMID:27525975] [Nature Methods]

Single-cell multimodal profiling reveals cellular epigenetic heterogeneity

“a method to genotype single cells while simultaneously interrogating gene expression and DNA methylation at multiple loci. We used this targeted multimodal approach, implemented on an automated, high-throughput microfluidic platform” “by profiling epigenetic variation among cell types identified through genotyping and transcriptional analysis.” Work from Stephen Quake.

Advertisements

Leave a Reply

Fill in your details below or click an icon to log in:

WordPress.com Logo

You are commenting using your WordPress.com account. Log Out / Change )

Twitter picture

You are commenting using your Twitter account. Log Out / Change )

Facebook photo

You are commenting using your Facebook account. Log Out / Change )

Google+ photo

You are commenting using your Google+ account. Log Out / Change )

Connecting to %s