Single-cell Epigenetic Heterogeneity

[PMID:27525975] [Nature Methods]

Single-cell multimodal profiling reveals cellular epigenetic heterogeneity

“a method to genotype single cells while simultaneously interrogating gene expression and DNA methylation at multiple loci. We used this targeted multimodal approach, implemented on an automated, high-throughput microfluidic platform” “by profiling epigenetic variation among cell types identified through genotyping and transcriptional analysis.” Work from Stephen Quake.


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