Single-cell Epigenetic Heterogeneity

[PMID:27525975] [Nature Methods]

Single-cell multimodal profiling reveals cellular epigenetic heterogeneity

“We used this targeted multimodal approach, implemented on an automated, high-throughput microfluidic platform, to assess primary lung adenocarcinomas and human fibroblasts undergoing reprogramming by profiling epigenetic variation among cell types identified through genotyping and transcriptional analysis. Work from Stephen Quake.

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