OmniPath

[PMID:27898060] [Nature Methods]

OmniPath: guidelines and gateway for literature-curated signaling pathway resources

“We performed a systematic analysis of public resources containing literature-curated human signaling interactions and also generated a large integrated resource, OmniPath” “OmniPath covers approximately three times more proteins (7,984) and four times more interactions (36,557) than the largest causal resource it contains. It covers ~39% of the human proteome, 61% of disease–gene associations, >80% of cancer-related genes and 54% of druggable proteins’

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