[PMID:28218898] [Nature Methods]
Detecting DNA cytosine methylation using nanopore sequencing
“By using synthetically methylated DNA, we were able to train a hidden Markov model to distinguish 5-mC from unmethylated cytosine.”
[PMID:28218897] [Nature Methods]
Mapping DNA methylation with high-throughput nanopore sequencing
“We map three cytosine variants and two adenine variants.”
Advertisements