Nanopore Methylation

[PMID:28218898] [Nature Methods]

Detecting DNA cytosine methylation using nanopore sequencing

“By using synthetically methylated DNA, we were able to train a hidden Markov model to distinguish 5-mC from unmethylated cytosine.”

[PMID:28218897] [Nature Methods]

Mapping DNA methylation with high-throughput nanopore sequencing

“We map three cytosine variants and two adenine variants.”

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