Comparison of Hi-C Algorithms

[PMID:28604721] [Nature Methods]

Comparison of computational methods for Hi-C data analysis

“We quantitatively compared the performance of 13 algorithms in their analyses of Hi-C data from six landmark studies and simulations. This comparison revealed differences in the performance of methods for chromatin interaction identification, but more comparable results for topologically associating domains (TAD) detection between algorithms.”

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