MAPPIN

[PMID: 28977528] [Nucleic Acids Research]

MAPPIN: a method for annotating, predicting pathogenicity and mode of inheritance for nonsynonymous variants

“a prediction method which utilizes a random forest algorithm to distinguish between nsSNVs with dominant, recessive, and benign effects.” “MAPPIN outperforms CADD and Eigen in predicting disease inheritance modes for all validation datasets. “

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